Types of Lynch Syndrome
Types of lynch syndrome include:
- Lynch syndrome I
- Lynch syndrome II
- Muir-Torre syndrome
What is Lynch I syndrome and Lynch II syndrome?
Lynch I syndrome is a term sometimes used to refer to families who have HNPCC with colorectal cancer only, while Lynch II refers to families who have other cancers, such as endometrial or ovarian, in addition to colorectal cancer.
What is Muir-Torre syndrome?
Muir-Torre syndrome is a rare variant of HNPCC in which the features of HNPCC are present along with sweat gland tumors, called sebaceous adenomas, and specific skin tumors, called keratoacanthomas. Like HNPCC, individuals with Muir-Torre syndrome are found to have mutations in either MSH2 or MLH1.