PET/MRI in the Diagnosis of Pediatric Chronic Pain
Trial ID or NCT#
Status
Purpose
\[18F\]FTC-146 is a sigma-1 receptor detector and is an experimental radiotracer. Several studies have implicated involvement of sigma-1 receptors in generation and perpetuation of chronic pain conditions, while others are investigating anti sigma-1 receptor drugs for treatment of chronic pain. Using \[18F\]-FTC-146 and PET/MRI, we hope to learn what is the best approach to identify the source of pain generation and characterize the disease in pediatric patients with chronic pain.
Official Title
Use of PET/MRI in the Diagnosis of Pediatric Chronic Pain
Eligibility Criteria
- * 11-18 years old.* Chronic pain (nociceptive, neuropathic or mixed pain) lasting at least 2 months.* Pain level of at least 4/10 on a 0-10 Comparative Pain Scale (reported at time of screening).* Covid Vaccination status: Vaccinated or unvaccinated subjects who received a negative test result from the Covid test within 72 hours of the scan.
- * MRI incompatible* Pregnant or nursing* Non-English speaker* Claustrophobic
Investigator(s)
View on ClinicalTrials.gov