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Comparison of simulated keratometric changes following wavefront-guided and wavefront-optimized myopic laser-assisted in situ keratomileusis
Comparison of simulated keratometric changes following wavefront-guided and wavefront-optimized myopic laser-assisted in situ keratomileusis CLINICAL OPHTHALMOLOGY Lee, W., Manche, E. E. 2018; 12: 613–19Abstract
The aim of the study was to determine and compare the relationship between change in simulated keratometry (K) and degree of refractive correction in wavefront-guided (WFG) and wavefront-optimized (WFO) myopic laser-assisted in situ keratomileusis (LASIK).A total of 51 patients were prospectively randomized to WFG LASIK in one eye and WFO LASIK in the contralateral eye at the Byers Eye Institute, Stanford University. Changes in simulated K and refractive error were determined at 1 year post-operatively. Linear regression was employed to calculate the slope of change in simulated K (?K) for change in refractive error (?SE). The mean ratio (?K/?SE) was also calculated.The ratio of ?K to ?SE was larger for WFG LASIK compared to WFO LASIK when comparing the slope (?K/?SE) as determined by linear regression (0.85 vs 0.83, p = 0.04). Upon comparing the mean ratio (?K/?SE), subgroup analysis revealed that ?K/?SE was larger for WFG LASIK for refractive corrections of >3.00 D and >4.00 D (0.89 vs 0.83; p = 0.0323 and 0.88 vs 0.83; p = 0.0466, respectively). Both linear regression and direct comparison of the mean ratio (?K/?SE) for refractive corrections <4.00 D and >4.00 D revealed no difference in ?K/?SE between smaller and larger refractive corrections.WFO LASIK requires a smaller amount of corneal flattening compared to WFG LASIK for a given degree of refractive correction. For both, there was no significant difference in change in corneal curvature for a given degree of refractive error between smaller and larger corrections.
View details for PubMedID 29636597