New to MyHealth?
Manage Your Care From Anywhere.
Access your health information from any device with MyHealth. You can message your clinic, view lab results, schedule an appointment, and pay your bill.
ALREADY HAVE AN ACCESS CODE?
DON'T HAVE AN ACCESS CODE?
NEED MORE DETAILS?
MyHealth for Mobile
Pharmacologic treatment for urgency-predominant urinary incontinence in women diagnosed using a simplified algorithm: a randomized trial
Pharmacologic treatment for urgency-predominant urinary incontinence in women diagnosed using a simplified algorithm: a randomized trial AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY Huang, A. J., Hess, R., Arya, L. A., Richter, H. E., Subak, L. L., Bradley, C. S., Rogers, R. G., Myers, D. L., Johnson, K. C., Gregory, W., Kraus, S. R., Schembri, M., Brown, J. S. 2012; 206 (5): 444.e1–11Abstract
The purpose of this study was to evaluate clinical outcomes associated with the initiation of treatment for urgency-predominant incontinence in women diagnosed by a simple 3-item questionnaire.We conducted a multicenter, double-blinded, 12-week randomized trial of pharmacologic therapy for urgency-predominant incontinence in ambulatory women diagnosed by the simple 3-item questionnaire. Participants (N = 645) were assigned randomly to fesoterodine therapy (4-8 mg daily) or placebo. Urinary incontinence was assessed with the use of voiding diaries; postvoid residual volume was measured after treatment.After 12 weeks, women who had been assigned randomly to fesoterodine therapy reported 0.9 fewer urgency and 1.0 fewer total incontinence episodes/day, compared with placebo (P = .001). Four serious adverse events occurred in each group, none of which was related to treatment. No participant had postvoid residual volume of = 250 mL after treatment.Among ambulatory women with urgency-predominant incontinence diagnosed with a simple 3-item questionnaire, pharmacologic therapy resulted in a moderate decrease in incontinence frequency without increasing significant urinary retention or serious adverse events, which provides support for a streamlined algorithm for diagnosis and treatment of female urgency-predominant incontinence.
View details for DOI 10.1016/j.ajog.2012.03.002
View details for Web of Science ID 000303211100029
View details for PubMedID 22542122
View details for PubMedCentralID PMC3570031