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The role of different subsets of T regulatory cells in controlling autoimmunity
The role of different subsets of T regulatory cells in controlling autoimmunity CURRENT OPINION IN IMMUNOLOGY Roncarolo, M. G., Levings, M. K. 2000; 12 (6): 676-683Abstract
T regulatory cells-in addition to clonal deletion and anergy-are essential for the downregulation of T cell responses to both foreign and self antigens, and for the prevention of autoimmunity. Recent progress has been made in characterising the different subsets of T regulatory cells, the factors that drive their differentiation, and their mode of action. The resolution of these mechanisms will make it possible to use T regulatory cells therapeutically in human autoimmune diseases.
View details for Web of Science ID 000165218000011
View details for PubMedID 11102772